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University Library, University of Illinois at Urbana-Champaign

Medical and Biomedical Research & Publication

Updated December 11, 2018

The changes to Common Rule are effective January 21, 2019. Information and clarifications about the revisions to the Common Rule are still being made available to the research community. We will update this page whenever new details that affect the information here are released. Please check back often to ensure you are always up to date.

Updated versions of the Protocol Form, Exempt Form, and all consent templates were made available on December 3, 2018 to be compliant with the revisions to the Common Rule.

About Research

About biomedical research:

The National Library of Medicine defines biomedical research as "research that is conducted to increase fundamental knowledge and understanding of the physical, chemical and functional mechanisms of human life processes and disease.


Basic research also known as fundamental or pure research is driven by a scientist’s curiosity or interest in a question. The main motivation of this type of research is to expand man’s knowledge of the world and not to invent or create something new. This area of research includes observation, description, measurement, and experimentation in order to better understand how living things work. Basic research forms the foundation of applied and clinical research.


Applied research is designed to address specific problems, rather than to just acquire knowledge or increase understanding. Applied research includes development of new drugs or procedures and can involve animals, humans, tissue cultures, or computer models.


Clinical research involves the study of human subjects to develop new diagnostic and therapeutic approaches that improve human health.